The SMART (Second Manifestations of ARTerial diseases) cohort started in 1996. It is an ongoing cohort study of patients with cardiovascular risk factors or clinically manifest arterial disease. The purpose is to screen these patients for vascular problems elsewhere in the body.
Patients with manifest arterial disease or a cardiovascular risk factor underwent vascular screening including a questionnaire, blood chemistry, and ultrasonography. All patients also fill out a biannual questionnaire in order to collect information on cardiovascular morbidity, mortality and diabetes mellitus end-points. In mid-2019, more than 13.500 people had completed the entire screening program.
See the UMC Utrecht website for more information about the SMART cohort.